Osteocalcin is an abundant noncollagenous bone matrix protein secreted by osteoblasts during bone formation. Through vitamin K-dependent γ-carboxylation of specific glutamic acid residues, osteocalcin binds hydroxyapatite with high affinity, comprising 10-20% of the total bone protein matrix.

ELISA kit information:

• Reactivity: Human
• Sample Type: Plasma, Tissue Homogenates, Serum, Biological Fluids
• Sensitivity: 0.094 ng/ml
• Target: ucOC, Undercarboxylated Osteocalcin